NFL Picks and Predictions – Week 17

Sep 21, 2014; Glendale, AZ, USA; San Francisco 49ers quarterback Colin Kaepernick (7) runs with the ball past Arizona Cardinals defensive end Kareem Martin (96) during the second half at University of Phoenix Stadium. The Cardinals won 23-14. Mandatory Credit: Joe Camporeale-USA TODAY Sports

Cardinals at 49ers

Winner:  49ers

Score prediction:       20-16  49ers 

Points spread:      49ers -6.5

Over/under:  37 – Under

4:25 pm – FOX     NFL Picks

Oct 19, 2014; St. Louis, MO, USA; Seattle Seahawks running back Marshawn Lynch (24) carries the ball while under pressure from St. Louis Rams strong safety T.J. McDonald (25) during the second half of a football game at the Edward Jones Dome. The Rams won 28-26. Mandatory Credit: Scott Kane-USA TODAY Sports

Rams at Seahawks

Winner:  Seahawks

Score prediction:       31-17  Seahawks

Points spread:      Seahawks -12

Over/under:  41 – Under

4:25 pm – FOX